Author

S. van Houte

3 papers indexed here

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Open access Sep 2026

Loss of restriction-modification methyltransferases drives persistence to fluoroquinolones in Pseudomonas aeruginosa

The resurgence of phage therapy has renewed interest in the interplay between phage resistance and antibiotic susceptibility1,2,3 and has stimulated research in the emergent field of non-canonical cellular functions carried out by defence systems4. Yet it remains largely unknown whether intracellular antiphage defence...

Maureen Micaletto, N. O. Gomez, A. Olina et al. · bioRxiv · 0 citations

Open access Sep 2026

PCR analysis of insertion sequences leads to the generation of artefact amplicons

Abstract Insertion sequences (ISs) are small, self-mobilizing DNA elements widespread across prokaryotic genomes, including chromosomes and plasmids. IS elements frequently co-localize with antimicrobial resistance (AMR) genes and mediate their mobilization, often as part of larger genomic structures that encompass mul...

Clàudia Morros-Bernaus, Ethan R. Wyrsch, S. Djordjevic et al. · Access Microbiology · 0 citations

Review Open access Sep 2026

Applications of transposon-insertion sequencing for understanding bacterial physiology

Tn-seq is particularly useful as a high-throughput method to assign function to function-unknown genes, which have increased steadily with the abundance of newly sequenced bacterial genomes.

E. Goodall, S. van Houte · Microbial Genomics · 0 citations