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S. Vtorushin

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Open access Oct 2026

Spatial Transcriptomic Profiling of FAP-Positive Cells in Gastric Cancer and Association with Immunotherapy Efficacy.

INTRODUCTION The spatial heterogeneity of the tumor microenvironment in gastric cancer, particularly in the stromal compartment, remains poorly characterized. Fibroblast activation protein (FAP)-positive cancer-associated fibroblasts (CAFs) are known to promote tumor progression, immune evasion, and therapeutic resista...

L. Tashireva, A. Kalinchuk, E. Shmakova et al. · 0 citations
Oct 2026

Well-differentiated liposarcoma of the pancreas: morphological features and surgical management in an elderly female patient

We report a rare clinical case of a well-differentiated liposarcoma (atypical lipomatous tumor), sclerosing subtype, arising from the pancreas in an 80-year-old female patient. The tumor initially presented as a painless bulging mass in the mesogastric region and, based on imaging studies, was interpreted as a lesion o...

E. Drozdov, S. Vtorushin, V. I. Kharitonkin et al. · 0 citations
Review Aug 2026

Predictors of immunotherapy response in gastric cancer: the role of the tumor microenvironment and integrative predictive models.

This review synthesizes current data on cellular, molecular, and systemic predictors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors, focusing on immune cell phenotypes, protein biomarkers, gene signatures, and metabolic factors.

E. Tsarenkova, A. Kalinchuk, E. Shmakova et al. · 0 citations

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