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Author

S. Woodman

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Open access Sep 2026

46 TKI Resistance is Associated with Immune Dysfunction in ccRCC

It is observed that sunitinib treatment leads to a marked reduction in endothelial cells and cancer‑associated fibroblasts, confirming a massive collapse of the vascular and perivascular niche, and identified two major tumor cell populations that adapt in distinct ways to sunitinib exposure and the resulting vascular c...

Xian-De Liu, Hong-Chao He, Jing-Jing Liu et al. · 0 citations
Jul 2026

Abstract A027: Leveraging genomic copy-number complexity in uveal melanoma to drive novel therapeutic development

It is demonstrated that uveal melanoma progression reflects an integrated CN-transcriptional ecosystem extending beyond chromosome 3 loss, with cytoband-level genomic evolution shaping malignant fitness and therapeutic response.

Johnathon L. Rose, Sanjana Srinivasan, A. Cooper et al. · 0 citations
Jul 2026

Abstract A053: Specific cancer cell and immune features mediate atezolizumab-regimen clinical benefit in anaplastic thyroid cancer (ATC) independent of BRAF or RAS oncogenic status

Specific differentiation and immune activation features are associated with longer OS, whereas mesenchymal, hypoxic, and proliferative programs are associated with shorter OS, whereas mesenchymal, hypoxic, and proliferative programs are associated with shorter OS.

Brian McKinley, Hai-Feng Zhu, Rare Tumor Initiative Team et al. · 0 citations

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