AIMS
Inflammation and structural brain alterations are implicated in psychosis risk, yet it remains unknown whether epigenetic C-reactive protein (CRP), a DNA methylation-based estimator of cumulative inflammatory burden, is associated with brain structure in youth at clinical high risk for psychosis (CHR-P).
METHODS...
B. Ku, Ying Xu, David R. Goldsmith et al.· Brain, behavior, and immunit...· 0 citations
Objective: Cognitive models of psychosis implicate maladaptive core schemas in the development and emergence of psychotic symptoms, but no study has tested temporal dynamics between schemas and psychotic symptoms in a large sample of clinical high-risk (CHR) youth. Given their sizable role in cognitive behavioral thera...
A. Broekhuijse, A. Saxena, C. Mourgues-Codern et al.· medRxiv· 0 citations
Modeling how functional network connectivity underlies transdiagnostic symptomatology has promised to advance psychiatric medicine by revealing neurobiological mechanisms related to comorbidity. However, network mapping methods have yet to yield clinically-actionable insights, largely due to complexities in the neurobi...
Alexander J. Simon, Santino Iannone, Anja Samardzija et al.· bioRxiv· 0 citations
Associations between patterns of brain connectivity and brain structural features have transdiagnostic relevance to psychopathology. There is considerable evidence for disruptions to the hippocampus and temporoparietal brain systems in psychotic disorders. The present study examines structure–function relationships—spe...
K. Aberizk, B. Ku, Heng-Yi Cao et al.· Brain Structure and Function· 0 citations
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