BACKGROUND
Oral squamous cell carcinoma (OSCC) is an aggressive malignancy with limited prognostic biomarkers, in which metabolic reprogramming contributes to tumor progression. Amino acid transporters of the solute carrier family have emerged as key regulators of cancer biology; however, the role of solute carrier fam...
L. Q. R. de Oliveira, E. F. de Morais, Cintia Eliza Marques et al.· Journal of Oral Pathology &...· 0 citations
BACKGROUND
Lymphovascular invasion (LVI) is a recognized poor prognostic factor in head and neck squamous cell carcinoma (HNSCC), particularly for regional recurrence and overall survival. However, its role in predicting distant metastasis, especially in HPV-negative HNSCC, remains unclear.
OBJECTIVE
To evaluate the...
M. Khoury, Alex Mlynarek, Keith Richardson et al.· Head and Neck· 0 citations
INTRODUCTION
Cancer cachexia is characterized by skeletal muscle loss, poor nutrition, and systemic inflammation and is common in head and neck cancer. We evaluated whether the Cachexia Index (CXI) predicts treatment toxicity and survival in HPV-negative HNSCC.
METHODS
This study included 353 patients undergoing cura...
G. Savoia, Michael P. Hier, Nader Sadeghi et al.· Head and Neck· 0 citations
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