Author

Shuo-Kai Zhang

2 papers indexed here

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Open access Oct 2026

Efficacy and safety of SYH2053 in patients with primary hypercholesterolemia or mixed dyslipidemia: a phase II, multicenter, randomized, double-blind, placebo- and active-controlled trial

SYH2053 is a novel small interfering RNA (siRNA) drug targeting proprotein convertase subtilisin/kexin type 9 (PCSK9), with optimized full-sequence chemical modification and N-acetylgalactosamine conjugation, which demonstrated a stable and sustained lipid-lowering efficacy in the phase I study in heathy particip...

F. Wang, Shu-Yi Zeng, S. Zhang et al. · European Heart Journal · 0 citations

Review Open access Sep 2026

Therapeutic Potential of Isoniazid in Inflammatory Skin Diseases: A Review

Therapeutic potential has been observed in conditions such as atopic dermatitis, psoriasis, urticaria, and rosacea, particularly among patients with latent tuberculosis infection or those undergoing biologic therapy, supporting its dual “anti-inflammatory–antituberculosis” value.

Shuo-Kai Zhang, Yi Tang, Jia-Ming Wen et al. · Clinical, Cosmetic and Inves... · 0 citations