Saar S. F. Van Overfelt

A phage-encoded host transcription modulator, Htm, reprograms the transcriptome of ESBL Escherichia coli

During phage infection, phages reprogram their host to secure energy, building blocks for their genome, and proteins, as well as the transcription and translation machinery required to replicate their genome and produce phage particles. This also includes reprogramming the host transcriptome to modify host gene express...