Sabine Merkelbach-Bruse

Brief report: Clinical and Functional Characterization of Rare Germline and Somatic EGFR Variants in Three Patients with Non-Small Cell Lung Cancer.

To date hereditary risk factors for non-small cell lung cancer (NSCLC) are poorly understood. While most cases are considered sporadic, rare monogenic germline alterations in EGFR and TP53 have been reported to be associated with increased risk of NSCLC. While identification and accurate functional characterization of...