Open access
Jul 2026
ESCAPE: assigning site-specific activity to covalent ligands in cells by prime editing
ESAPE (Endogenous Site-specific Competition Assays using Prime Editors using Prime Editors), a platform for the site-resolved functional analysis of covalent ligands in cells, identifies multiple covalent ligand-protein interactions that impair cancer cell growth.
Jason Tse, William R. Brothers, Rachel E. Hayward et al.
· bioRxiv · 0 citations