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Sabrina Golusik

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Open access Sep 2026

Ligand-induced activation of RyR1 in native membranes

Synchronized calcium release through arrays of the ryanodine receptor RyR1, fundamental to skeletal muscle excitation-contraction coupling, is achieved through the mechanical interaction of RyR1s and voltage-sensing receptors DHPR that activate RyR1s in response to action potentials. The calcium release is enhanced thr...

Vasilii Mikirtumov, Sabrina Golusik, Rui-Feng Huo et al. · 0 citations

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