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Sagrario Ortega

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Open access Jul 2026

Contribution of cohesins STAG1 and STAG2 to preimplantation development in mice.

Cohesin complexes carrying either STAG1 or STAG2 display functional specificities in both cohesion and genome organization. While any variant is sufficient for cell viability, both are essential for murine embryonic development, and mutations in STAG1 and STAG2 are associated to human syndromes. The requirements and re...

Maria Solé-Ferran, Maria Jose Andreu, D. Giménez-Llorente et al. · 0 citations

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