HOPS and Vps13 Have Antagonistic Roles in Regulating Lipid Droplet Morphology
Lipid droplets are dynamic organelles that store neutral lipids (mostly triacylglycerols and sterol esters) and are bound by a single phospholipid monolayer. The formation and breakdown of the droplets are important for cellular metabolism; however, the molecular mechanisms regulating their biogenesis and turnover are...