Single cell mapping of B and T cell dynamics in breast cancer lymph node metastasis
An integrated meta-analysis of single cell RNA-seq datasets from normal breast tissue, primary tumors, tumor-draining lymph nodes, and peripheral blood mononuclear cells defines niche specific lymphocyte remodeling and implicate BTLA-HVEM and CXCL12-CXCR4 as candidate biomarkers and therapeutic targets linked to PD-1/P...