Twin study: genotype-dependent epigenetic factors associated with HbA1c levels.
BACKGROUND Hemoglobin A1c (HbA1c) is a biomarker for diabetes mellitus. Twin studies suggest substantial heritability, but the molecular basis of non-genetic variation remains unclear. We aimed to explore genetic and epigenetic factors associated with HbA1c through multi-omics analysis of monozygotic twins. MATERIALS...