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The immunophenotype and proviral landscape of HIV-infected CD4 T cells during antiretroviral therapy
Significance The persistence of HIV in CD4+ T cells during antiretroviral therapy (ART) remains a barrier to cure. To study this reservoir, we developed an open-source DAb-seq platform that sequences proviral DNA and surface epitopes in single cells and profiled ~527,000 CD4 T cells from individuals on ART. HIV-infecte...