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Author

Saleh Almutairi

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Sep 2026

Beyond Symmetric Motifs: Asymmetric Small-Molecule Recognition Directs a New Poly(adenine) Assembly

DNA/small-molecule hybrid materials provide a powerful route to reprogram nucleic acid structures without covalent modification. However, to date only two small molecules have been shown to direct such assemblies, both relying on symmetric hydrogen-bonding faces. Here, we report that 3-methylxanthine (3MeX), a purine...

Jessica Bennett, Christophe Lachance-Brais, Saleh Almutairi et al. · 0 citations

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