Curcumin-loaded lipid nanoparticles for photodynamic therapy in the topical treatment of melanoma.
Melanoma remains one of the deadliest skin cancers, and current therapies still struggle to combine efficacy with minimal invasiveness. Photodynamic therapy (PDT) is a promising alternative, yet its translation is hindered by poor photosensitizer (PS) solubility and difficulty achieving effective localized skin deliver...