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Author

Salla Kyheröinen

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Review Open access Sep 2026

A guide to transcriptional cyclin-dependent kinases in cancer.

Transcriptional cyclin-dependent kinases (tCDKs) are master regulators of gene expression, controlling RNAPII activity and RNA synthesis across multiple phases of the transcription cycle. While highly controlled transcription is essential for all cellular processes and functions, aberrant gene expression or corrupted a...

J. Devlin, Salla Kyheröinen, Ricky W. Johnstone · 0 citations

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