Aug 2026
Design, one-pot synthesis, and structural characterization of novel 2-ureido-6-nitrobenzamide derivatives as MTDLs targeting HDAC8/epigenetic-kinase networks.
These tunable 2-ureido-6-nitrobenzamide scaffold serves as an in silico prioritization starting point for the rational design of dual-action therapeutics targeting complex oncology and neurodegenerative networks, requiring future in vitro and in vivo validation.
M. Farouk, Salsabil Mahmoud, A. Imran et al.
· Bioorganic chemistry (Print) · 0 citations