Review
Open access
Sep 2026
Oncofetal antigens as emerging targets in chimeric antigen receptor (CAR)-T cell-based immunotherapies: opportunities and challenges
It is proposed that integrating principles from developmental biology, tumor evolution, and immuno-engineering will be essential to unlocking the therapeutic potential of oncofetal antigen-directed CAR-T therapies in solid tumors.
Sam Sebastian Smith, A. Klampatsa
· Frontiers in Cell and Develo... · 0 citations