Author

Samantha D. Patalano

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Open access Apr 2026

Intragenic transcription from defective HIV proviruses triggers interferon responses in myeloid cells

It is proposed that defective HIV proviruses contribute to chronic inflammation in PWH through an MDA5-dependent induction of type I interferon pathways.

Jonathan Kilroy, Aparna A. Deokar, Samantha D. Patalano et al. · bioRxiv · 0 citations