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Samantha Delia Crist

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O'6-methylguanine-DNA methyltransferase methylation status in canine intracranial glioma tissue samples

Gliomas are the second most common intracranial malignancy in dogs. Methylation of the CpG island of the MGMT (O6-methylguanine-DNA-methyltransferase) gene has been associated with an increased clinical response to temozolomide in human glioma. CpG island methylation can silence a gene responsible for a pathway of DNA...

Samantha Delia Crist · 0 citations

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