Tree-Based Classification of COVID-19 Using NanoString Whole-Blood Immune-Response Profiles: Comparison of Full-Dataset and LOOCV-Embedded Feature Selection
Background: Whole-blood transcriptomic profiling can capture systemic immune-response alterations associated with COVID-19 and may support host-response-based classification. However, evidence regarding the discriminatory value of targeted immune-gene panels remains limited, and in small, high-dimensional datasets, the...