It is demonstrated that FleN dosage is essential for maintaining monoflagellation and fitness, holding P. aeruginosa at a single flagellum while retaining the latent capacity to reach multiflagellated states through single mutations.
Analí Migueles-Lozano, Merrill Asp, Sofia T Rocha et al.· mBio· 0 citations
Swarm-seq is established as a powerful platform for characterizing CsrA homologs from genetically intractable or unculturable bacteria and the potential for machine learning-guided discovery of functional regulatory proteins is demonstrated, providing insights into post-transcriptional regulatory network evolution.
Jared T. Winkelman, Ethan Yarberry, Georgia Fanouraki et al.· Nucleic Acids Research· 0 citations
Current understanding of predatory mechanisms, environmental roles, and biotechnological potential of Bdellovibrio are synthesized while identifying key knowledge gaps: the regulatory logic governing life cycle transitions, molecular determinants of host range, and predator-prey population dynamics.
Sampriti Mukherjee, A. Lovering· Annual Review of Microbiolog...· 0 citations
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