Author

Samuel A. Manning

2 papers indexed here

We haven’t gathered this author’s papers yet. Follow them and we’ll fetch their work.

Not the right person? Other researchers publish under this name.

Open access Sep 2026

The Hippo signalling pathway regulates the timing of epithelial cell replacement during Drosophila abdominal morphogenesis

ABSTRACT Developmental apoptosis plays an important role in shaping the organs of developing animals, such as occurs during the development of the adult fly abdomen, in which the apoptosis of larval epidermal cells (LECs) is delicately balanced with the proliferation of the presumptive adult epithelial cells. The signa...

Kyle Lyon, Samuel A. Manning, R. Burke · Journal of Cell Science · 0 citations

Open access Aug 2026

The mechanosensitive protein Zyxin influences Hippo signaling and tissue growth via adherens junctions and basal spot junctions in Drosophila.

Mechanical forces such as tension and compression play a central role in the growth and morphogenesis of tissues. Cell-cell junctions and the actin cytoskeleton are key mediators of mechanical forces and influence the activity of signaling networks, including the Hippo pathway. Here, we show that the mechanosensitive p...

Harmanjeet Singh, Elliot Brooks, Connor Keegan et al. · Current Biology · 1 citation