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Author

Samuel B. Warner

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Open access Sep 2026

Balancing lipid synthesis and oxidation promotes B cell response to vaccination during immunosuppression.

Pharmacologic immunosuppression is essential for preventing organ rejection and controlling autoimmunity, but profoundly impairs humoral immunity, increasing the risk of vaccine failure and infection. The mechanisms by which immunosuppressive therapies disrupt human B cell responses remain poorly defined. Here, we iden...

Elizabeth A. Thompson, Alexis Figueroa, Katerina Roznik et al. · 0 citations
Open access Sep 2026

An altered B cell compartment distinguishes low antibody responders among people with HIV

Chronic HIV infection can leave persistent immune dysregulation despite effective antiretroviral therapy (ART), but how this altered immune landscape affects antibody induction and durability after antigen exposure remains unclear. We used SARS-CoV-2 infection and vaccination as a model of humoral immunity to a novel a...

Karli R. Redinger, Samuel B. Warner, A. Jamal et al. · 0 citations
Open access Jul 2026

CpG-Adjuvanted Heplisav-B Induces Strong Th1-Biased Innate Responses Compared to Alum-Adjuvanted HBV Vaccines in PLWH 2308661

Heplisav-B induces stronger Th1-skewed innate responses and increased B cell frequency than Engerix-B in PLWH within the first 24 hours of vaccination, while overall cellular composition and activation remain largely preserved.

Jenny M. Lee, Prasanthy Balasubramanian, Yufeng Liu et al. · 0 citations

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