Microbiome-Derived RNA as a Trigger for Heritable Innate Immunity 2252988
The microbiome shapes host immunity, yet the molecular signals by which specific bacteria modulate innate defenses remain poorly understood. In Caenorhabditis elegans, the Intracellular Pathogen Response (IPR) is a transcriptional program activated by obligate intracellular pathogens and shares features with mamm...