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Author

Samuel Lobo

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Open access Sep 2026

A water-pinning hotspot drives templated tau aggregation

Tau assembles into fibrillar aggregates that are pathological hallmarks of a group of neurodegenerative diseases collectively called tauopathies. Templated aggregation of naïve tau to seeding-competent fibrils that proceed from cell to cell is a key driver of prion-like progression of tauopathies. This study tests the...

Chung-Ta Han, Karen Tsay, Samuel Lobo et al. · 0 citations

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