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Sana Ismaeel

1 paper indexed here

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Open access Jul 2026

TRIM21 Orchestrates Inflammasome Assembly and Drives Autoinflammatory Pathology 2300561

Inflammasomes are pivotal cytoplasmic scaffolds that drive the maturation of interleukin (IL)-1β and IL-18 and initiate pyroptotic cell death. Tight regulation of inflammasome activity is critical, as uncontrolled IL-1β release underlies chronic inflammation and autoinflammatory disease. The adaptor protein ASC i...

Jessica Carriere, Chawon Yun, Sonal Khare et al. · 0 citations

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