Structural features, activity relationships, and synthetic strategies of indole-based derivatives as antitubercular agents targeting mycolic acid biosynthesis
Tuberculosis (TB) is a severe airborne infectious disease caused by Mycobacterium tuberculosis ( M. tb ), primarily impacting the lungs and other organs. Antimicrobial resistance in TB is an emerging problem that requires immediate treatment and management. It is difficult to cure tuberculosis as there are increa...