Mapping the Mutational Landscape of Myeloproliferative Neoplasms: An Indian Cohort of 1,000 Patients
Abstract Introduction Myeloproliferative neoplasms (MPNs) are clonal hematopoietic stem cell disorders characterized by overproduction of myeloid lineages. Driver mutations in JAK2 , CALR , and MPL account for most cases; however, additional somatic mutations contribute to disease heterogeneity, prognosis, and therapeu...