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Author

Sandra Moreno

2 papers indexed here

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Review Open access Sep 2026

From Amyloid Exposure to Genetic Causality: Converging hiPSC-Based Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder in which genetic susceptibility, aging, protein aggregation, and neuroglial dysfunction converge to drive progressive neuronal loss. Although animal models and conventional cell systems have provided fundamental insights into pathomechanisms, they only partially...

Fiorella Colasuonno, Alessio Valenza, F. Rossin et al. · 0 citations
Open access Jul 2026

Pharmacological modulation of p75 neurotrophin receptor in microglial cells improves resilience to rotenone cytotoxicity

The findings demonstrate that pharmacological modulation of p75NTR by LM11A-31 protects microglial cells against Rot-induced cytotoxicity and inflammatory activation, and may represent a promising therapeutic strategy to counteract microglial dysfunction and neuroinflammatory processes associated with Parkinson’s disea...

Alessio Valenza, D. Pensabene, Francesca Rendina et al. · 1 citation

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