ARTICLE HIGHLIGHTS
The innate immunity receptor nucleotide-binding oligomerization domain 1 (Nod1) can be activated by saturated fatty acids and is implicated in high-fat diet-induced inflammation and insulin resistance. This implies Nod1 plays a role in glucose homeostasis; therefore, we sought to determine whether sa...
J. Yung, Emily G. Hoffman, A. Ivovic et al.· Diabetes· 0 citations
Antipsychotics represent mainstay treatment of schizophrenia and are also prescribed on- and off-label in other severe mental illnesses. Newer antipsychotic use is associated with severe metabolic side effects such as obesity and type 2 diabetes. Leptin is a hormone secreted by adipose tissue, and it acts on the brain...
Raghunath Singh, R. Asgariroozbehani, Sally Wu et al.· Neuropharmacology· 0 citations
Atherosclerosis, a chronic inflammatory disease of the arteries, is the primary cause of ischemic heart disease and stroke, which are the leading drivers of global mortality and major contributors to disability. Important risk factors for atherosclerosis include insulin resistance (IR), hypertension and hyperlipidemia....
Qiu-Wang Zhang, Yin-Gen Chen, Di Wang et al.· Frontiers in Medicine· 0 citations
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