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Sang-Hoon Lee

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Open access Sep 2026

Smoking-Associated Enrichment of CXCL13+ Tfh Cells and VCAM1+ Fibroblasts Is Linked to Tertiary Lymphoid Structure Formation in Lung Adenocarcinoma

Smoking-associated enrichment of CXCL13⁺CD4⁺ Tfh cells was associated with B-cell accumulation and TLS formation in LUAD, and these findings identify the CXCL13⁺ Tfh-B-cell axis, together with VCAM1⁺ fibroblast-rich stromal niches, as potential biomarkers and therapeutic targets in LUAD.

Y. Choi, Chi Young Kim, Eun Young Kim et al. · 0 citations

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