Open access
Jul 2026
Molecular Mechanisms Underlying FCCP-Induced Mitophagy in Human Airway Smooth Muscle Cells
It is hypothesized that FCCP-induced mitochondrial depolarization activates the PINK1-Parkin-mediated mitophagy pathway, culminating in the clearance of damaged mitochondria, and these findings demonstrate that FCCP robustly activates the canonical PINK1-Parkin mitophagy pathway in hASM cells.
Sanjana Mahadev Bhat, Oscar A. Ramirez Ramirez, G. Sieck
· American Journal of Physiolo... · 0 citations