Preprint
Aug 2026
Predicting Early Functional Decline from Longitudinal Laboratory and Vital Sign Trajectories: A Large-Scale Study Using the All of Us Research Program
Functional decline in older adults is typically recognized only after falls or observable gait impairment, closing the window for prevention. We investigated whether temporal trajectories of routine biomarkers, already recorded but rarely analyzed longitudinally, can identify patients in the pre-clinical phase of mobil...
Rashmita Kudamala, Aravind V. Kuruvikkattil, Lalitha Pranathi Pulavarthy et al.
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