Sara Fin

Structural, Functional and Cognitive Validation of a Deep-Learning MCI-to-AD Conversion Model in OASIS-3

Background. Deep-learning models predict mild cognitive impairment (MCI)-to-Alzheimer's disease (AD) conversion from structural MRI with high accuracy. However, they are typically validated within a single cohort and judged on discrimination alone. Whether their risk scores are biologically grounded, and whether they g...