Sarah A. Revitt-Mills

Virulence on the move: toxin plasmids drive diversity and disease in Clostridium perfringens

Advances in the understanding of toxin diversity and plasmid biology in C. perfringens are reviewed, highlighting the remarkable plasticity of its mobile genome and positioning C. perfringens as a compelling model to understand how mobile genetic elements drive virulence, adaptation and disease in bacterial pathogens.