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Sarah M. Leichter

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Oct 2026

Profiling Active Regulatory Elements in Archival Mouse Tissue by Formalin-Fixed Paraffin-Embedded Cleavage Under Targeted Accessible Chromatin.

The standard for long-term storage of tissue samples is formalin fixation and paraffin embedding (FFPE), a method that allows samples to be archived at room temperature for decades. However, RNA degrades during storage, and prolonged exposure to ~4% formaldehyde damages RNA and DNA, limiting the utility of RNA sequenci...

Elena Lill, Emily Dinh, Mehar Dhami et al. · 0 citations

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