Open access
Sep 2026
Evidence for similar enzymatic but different cellular generation of pE79-modified α-synuclein in PD and AD mouse models.
The α-synuclein (aSyn) pathology is a predominant feature of synucleinopathies such as Parkinson's disease (PD). Triggers that may induce aSyn aggregation are not completely understood, but include post-translational modifications. One such modification is aSyn truncation exposing the N-terminal glutamine 79 residue th...
A. Bluhm, Merle Großmann, Charlotte Minister et al.
· Neurochemistry International · 0 citations