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Author

Sarah Youssef

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Open access Oct 2026

Topographical features enhance DNA tetrahedron biostability

Stabilization of nucleic acid-based systems is critical for their clinical translation in biomedical applications. Here, we integrated hairpins within the edges of a DNA tetrahedron and studied the stabilization induced by these motifs against nucleases. We show that nuclease resistance of DNA tetrahedra increased with...

Sarah Youssef, Lauren A. Anderson, Meng-Yao Zheng et al. · 0 citations
Open access Sep 2026

DNA Nanotechnology in the Undergraduate Laboratory: Isothermal Assembly and Quantification of DNA Nanostructures

DNA nanotechnology has proven to have strong potential in several applications. This technology relies on the programmable nature of DNA self-assembly to build structures and motifs with a high level of precision. Most assembly techniques rely on a temperature gradient that might not be suitable for all applications, e...

Hannah Talbot, Sarah Youssef, A. Chandrasekaran · 0 citations

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