FORMULATION AND QBD-BASED OPTIMIZATION OF CHITOSAN-COATED NANOSTRUCTURED LIPID CARRIERS FOR ENHANCED DRUG DELIVERY OF AZILSARTAN MEDOXOMIL
Objective: Azilsartan medoxomil (AZM) is a Class II antihypertensive drug with poor aqueous solubility that limit its dissolution and oral performance. The aim of present investigation was to improve its dissolution properties by formulating chitosan-coated AZM NLCs (CH-NLCs) and optimizing using QbD approach. Methods:...