The Glymphatic System in Traumatic Brain Injury, Subarachnoid Hemorrhage, and Neurodegeneration: A Unifying Neurobiological Framework
Whether glymphatic dysfunction drives or merely follows brain injury and neurodegeneration remains unresolved. The glymphatic system mediates the transport, exchange, and clearance of solutes between cerebrospinal fluid (CSF) and interstitial fluid (ISF) through paravascular CSF influx, polarized aquaporin-4 (AQP4) at...