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Author

Satheeshkumar Nagaraj

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Aug 2026

Rapid, Sequential Synthesis of 5-Acetoxy-1-Substituted Tetrazoles Via Heterogeneous FeCl3-Al2O3 Catalysis and Hypervalent Iodine Functionalization

The 1,5-disubstituted tetrazole moiety is a critical pharmacophore in medicinal chemistry, valued as a metabolically stable carboxylic acid bioisostere. Existing synthetic routes often suffer from slow kinetics, high costs, or harsh conditions. We report a rapid, sustainable protocol for synthesising 5-acetoxy-1-su...

Satheeshkumar Nagaraj, Karpagam Ezhilarasan, Gopalakrishnan Mannathusamy et al. · 0 citations

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