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Author

Satoshi Waguri

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2 papers indexed here

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Review Oct 2026

BNIP3/NIX-mediated mitophagy versus Parkin-mediated mitophagy: mechanistic differences and functional implications.

Mitophagy is a form of selective autophagy in which an isolation membrane (IM or phagophore) sequesters damaged or superfluous mitochondria for lysosomal degradation. Recent advances in receptor-mediated mitophagy, particularly the BNIP3/NIX-mediated mitophagy, have highlighted the importance of this pathway in mitocho...

Satoshi Waguri, S. Yamashita, Ritsuko Arai et al. · 0 citations
Open access Aug 2026

Sorting of lysosomal enzyme and autophagy are regulated by the GGA1-induced TGN lipid scrambling

The physiological role of lipid asymmetry in intracellular membranes remains poorly understood. Here, we show that sphingomyelin (SM), typically confined to the lumen of the trans-Golgi network (TGN), is exposed on its cytoplasmic surface by the action of the Golgi-associated protein, Golgi-associated gamma-adaptin ear...

Kohta Takahashi, Nario Tomishige, Mitsuhiro Abe et al. · 0 citations

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