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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Satyaki Saha

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Open access Aug 2026

A Minimalist Model for Navigating Conformational Landscape Uncovers the Activation Mechanism of β2‑Adrenergic Receptor

A mechanistic understanding of GPCR activation is essential to designing modulators for its function. The lower energy of the inactive state under basal conditions, as well as the transient nature of intermediates have impeded the characterization of GPCR’s activation mechanisms at full-atomic scale. In this study, we...

Satyaki Saha, Anthony T. Bogetti, Ivet Bahar · 0 citations

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