Open access
Sep 2026
Discovery of novel acridine based inhibitors of Bruton’s tyrosine kinase (BTK) via pharmacophore modeling and machine learning-driven virtual screening followed by molecular dynamic studies
A key outcome of this study is the identification of a chemically distinct and novel, acridine-based antiproliferative hit candidates with measurable BTK inhibitory activity.
Rand O. Shahin, Sawsan Jaafreh, Iman A. Mansi et al.
· Journal of Computer-Aided Mo... · 0 citations