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Sayantan Sarkar

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Aug 2026

Immobilization of Novel l -asparaginase Variants on Functionalized Multiwalled Carbon Nanotubes Improves Stability, Resistance to Proteolytic Degradation, and Prolonged Antileukemic Activities

Escherichia coli-derived l-asparaginase (EcA) is a crucial frontline therapy for the treatment of acute lymphoblastic leukemia (ALL), yet its use in clinical settings remains considerably compromised due to its immunogenicity, hypersensitivity reactions, hepatotoxicity, rapid proteolytic degradation, and a markedly s...

B. Nayak, Sukanya Samanta, Sayantan Sarkar et al. · 0 citations

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