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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Scott A. Jackson

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Open access Jul 2026

CASCADE recovers promoter-associated regulatory motifs from cell-type-resolved DNA language-model attributions

ContextAware Significance of Cross-gene Attribution for Discovering Elements (CASCADE) is introduced, a positionspecific statistical framework for identifying model-derived candidate regulatory elements from in silico saturation mutagenesis and shifts motif recovery from downstream of the transcription start site toward promoter sequence.

Ali Farghadan, Robert J. Schmitz, Scott A. Jackson et al. · 0 citations

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