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Author

Scott E. Evans

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Open access Sep 2026

Apoptosis inhibition reprograms alveolar myofibroblasts toward ductal myofibroblasts.

The epithelial tree of the lung is shaped proximo-distally by airway smooth muscle cells (ASMCs), ductal myofibroblasts (DMFs), and, transiently, alveolar myofibroblasts (AMFs). Lineage tracing and snapshot imaging suggest the clearance of AMFs via apoptosis post-alveologenesis, although definitive evidence is lacking....

M. Gacha-Garay, Hui Liu, Scott E. Evans et al. · 0 citations
Open access Aug 2026

HIF1A-dependent induction of alveolar miR-147b dampens SARS-CoV-2-associated ARDS via direct targeting of viral RNA.

Alveolar epithelial cell-derived miR-147b serves as an endogenous lung protective miRNA against SARS-CoV-2-associated ARDS by directly targeting virus-encoded RNA, revealing a previously unrecognized antiviral and lung-protective mechanism.

Xiao-Yi Yuan, Jieun Kim, K. Figarella et al. · 0 citations

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